L-Pyrohomoglutamic acid
Based on 1 Customer Validation
L-Pyrohomoglutamic acid is an amino acid building block. L-Pyrohomoglutamic acid can be used to synthesize ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors.
For research use only. We do not sell to patients.
- Purity: 99.51%
- CAS No.: 34622-39-4
- Formula: C6H9NO3
- Molecular Weight:143.14
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 34622-39-4
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Appearance Solid
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Molecular Weight 143.14
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Formula C6H9NO3
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Color White to light brown
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SMILES
O=C([C@H](CCC1)NC1=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 40 mg/mL (279.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Pomplun S, et al. Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs). Angew Chem Int Ed Engl. 2015 Jan 2;54(1):345-8. [Content Brief]
[2]. Taddei M, et al. Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitors. Bioorg Med Chem Lett. 2014 Jan 1;24(1):61-4. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.9862 mL | 34.9308 mL | 69.8617 mL | 174.6542 mL |
| 5 mM | 1.3972 mL | 6.9862 mL | 13.9723 mL | 34.9308 mL | |
| 10 mM | 0.6986 mL | 3.4931 mL | 6.9862 mL | 17.4654 mL | |
| 15 mM | 0.4657 mL | 2.3287 mL | 4.6574 mL | 11.6436 mL | |
| 20 mM | 0.3493 mL | 1.7465 mL | 3.4931 mL | 8.7327 mL | |
| 25 mM | 0.2794 mL | 1.3972 mL | 2.7945 mL | 6.9862 mL | |
| 30 mM | 0.2329 mL | 1.1644 mL | 2.3287 mL | 5.8218 mL | |
| 40 mM | 0.1747 mL | 0.8733 mL | 1.7465 mL | 4.3664 mL | |
| 50 mM | 0.1397 mL | 0.6986 mL | 1.3972 mL | 3.4931 mL | |
| 60 mM | 0.1164 mL | 0.5822 mL | 1.1644 mL | 2.9109 mL | |
| 80 mM | 0.0873 mL | 0.4366 mL | 0.8733 mL | 2.1832 mL | |
| 100 mM | 0.0699 mL | 0.3493 mL | 0.6986 mL | 1.7465 mL |
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