357645-16-0
357645-16-0
Chemical Structure
Vitexin B-1
- CAS No.: 357645-16-0
- Formula:C20H20O6
- Molecular Weight:356.37
IUPAC Name: (3R,4S)-6-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-3,4-dihydronaphthalene-2-carbaldehyde
InChIKey: PATMJUOZIPKVAS-YWZLYKJASA-N
SMILES: OC[C@@H]1[C@@H](C2=CC(OC)=C(O)C=C2)C3=CC(O)=C(OC)C=C3C=C1C=O
Biological Activity: Vitexin B-1 is an inhibitor of Bcl-2 and the agonist of Caspase. Vitexin B-1 has cytotoxic effect and induces apoptosis in MCF-7, ZR-75-1, MDA-MB-231, and COC1 cells with IC50s of 3.2, 2.1, 1.8 and 0.39 μM, respectively[1].
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Vitexin B-1 | Vitexin B-1 is an inhibitor of Bcl-2 and the agonist of Caspase. Vitexin B-1 has cytotoxic effect and induces apoptosis in MCF-7, ZR-75-1, MDA-MB-231, and COC1 cells with IC50s of 3.2, 2.1, 1.8 and 0.39 μM, respectively. | |||||||||||||||||||||
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References
Keywords
