Vitexin B-1
Vitexin B-1 is an inhibitor of Bcl-2 and the agonist of Caspase. Vitexin B-1 has cytotoxic effect and induces apoptosis in MCF-7, ZR-75-1, MDA-MB-231, and COC1 cells with IC50s of 3.2, 2.1, 1.8 and 0.39 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 357645-16-0
- Formula: C20H20O6
- Molecular Weight:356.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
3.54 μM
Compound: 7
|
Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess reagent method
Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess reagent method
|
[PMID: 19715321] |
Chemical Information
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CAS No. 357645-16-0
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Molecular Weight 356.37
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Formula C20H20O6
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SMILES
OC[C@@H]1[C@@H](C2=CC(OC)=C(O)C=C2)C3=CC(O)=C(OC)C=C3C=C1C=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)