361457-01-4
361457-01-4
Chemical Structure
RO3244794
- CAS No.: 361457-01-4
- Formula:C25H19F2NO5
- Molecular Weight:451.42
InChIKey: IDONYPMIPXYFLY-JOCHJYFZSA-N
SMILES: FC(C=C1)=CC=C1C[C@H](C(O)=O)NC(OCC2=CC3=CC(C4=CC=C(C=C4)F)=CC=C3O2)=O
Biological Activity: RO3244794 is a potent and selective IP (prostacyclin) receptor antagonist, with a pKi of 7.7 and 6.9 in human platelet and recombinant IP receptor system, respectively. RO3244794 exhibits analgesic and anti-inflammatory potential[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RO3244794 | 99.64% | RO3244794 is a potent and selective IP (prostacyclin) receptor antagonist, with a pKi of 7.7 and 6.9 in human platelet and recombinant IP receptor system, respectively. RO3244794 exhibits analgesic and anti-inflammatory potential. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.57
HY-W008995Fmoc-Phe(4-F)-OH -
Similarity Score 0.57
HY-W008996Fmoc-D-Phe(4-F)-OH -
Similarity Score 0.55
HY-W011154Z-D-2-Nal-OH -
Similarity Score 0.55
HY-W088147Z-L-2-Nal-OH -
Similarity Score 0.55
HY-W010836Fmoc-Bip(4,4')-OH -
Similarity Score 0.55
HY-W010838Fmoc-D-Bip(4,4’)-OH -
Similarity Score 0.54
HY-W010926Fmoc-Phe(3,4-DiF)-OH -
Similarity Score 0.54
HY-W013123Fmoc-D-Phe(4-CF3)-OH -
Similarity Score 0.54
HY-155417GPR34 receptor antagonist 3 -
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