361457-01-4
361457-01-4
Chemical Structure
RO3244794
- CAS No.: 361457-01-4
- Formula:C25H19F2NO5
- Molecular Weight:451.42
InChIKey: IDONYPMIPXYFLY-JOCHJYFZSA-N
SMILES: FC(C=C1)=CC=C1C[C@H](C(O)=O)NC(OCC2=CC3=CC(C4=CC=C(C=C4)F)=CC=C3O2)=O
Biological Activity: RO3244794 is a potent and selective IP (prostacyclin) receptor antagonist, with a pKi of 7.7 and 6.9 in human platelet and recombinant IP receptor system, respectively. RO3244794 exhibits analgesic and anti-inflammatory potential[1].
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RO3244794 | 99.64% | RO3244794 is a potent and selective IP (prostacyclin) receptor antagonist, with a pKi of 7.7 and 6.9 in human platelet and recombinant IP receptor system, respectively. RO3244794 exhibits analgesic and anti-inflammatory potential. | ||||||||||||||||||||
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References
Keywords
