362043-77-4
Chemical Structure
P160 peptide
- CAS No.: 362043-77-4
- Formula:C74H105N17O17S
- Molecular Weight:1536.79
InChIKey: WXOHJWHNEMTSAT-YZVGNEOXSA-N
SMILES: O=C([C@H]1N(CCC1)C([C@@H](N)C(C)C)=O)N[C@H](C(N[C@@H](CCSC)C(N[C@@H](CCC(O)=O)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CC3=CC=CC=C3)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56
Biological Activity: The P160 peptide is a breast cancer-targeting peptide that binds to the keratin 1 (KRT1) receptor on breast cancer cells, with a Kd of approximately 1.1 μM, demonstrating significant potential for targeted drug delivery to breast cancer cells. The P160 peptide enhances the cellular uptake and anticancer activity of the pro-apoptotic antimicrobial peptide MccJ25 (microcin J25). The P160 peptide can be used in cancer research[1].
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P160 peptide | The P160 peptide is a breast cancer-targeting peptide that binds to the keratin 1 (KRT1) receptor on breast cancer cells, with a Kd of approximately 1.1 μM, demonstrating significant potential for targeted drug delivery to breast cancer cells. The P160 peptide enhances the cellular uptake and anticancer activity of the pro-apoptotic antimicrobial peptide MccJ25 (microcin J25). The P160 peptide can be used in cancer research. | |||||||||||||||||||||
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Keywords
