364735-73-9
364735-73-9
Chemical Structure
CDK2-IN-18
- CAS No.: 364735-73-9
- Formula:C21H23N7O2S
- Molecular Weight:437.52
InChIKey: KRKQVGZXTNLQSV-UHFFFAOYSA-N
SMILES: O=C(NN1CCN(CC1)C)NC2=CC=CC(C3=NNC(C4=C(C)N=C(C)S4)=C35)=C2C5=O
Biological Activity: CDK2-IN-18 (compound 8q) is a potent inhibitor of CDK2/E and CDK4/D1, with IC50s of 8 nM and 46 nM, respectively. CDK2-IN-18 inhibits the proliferation of tumor cells[1].
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CDK2-IN-18 | CDK2-IN-18 (compound 8q) is a potent inhibitor of CDK2/E and CDK4/D1, with IC50s of 8 nM and 46 nM, respectively. CDK2-IN-18 inhibits the proliferation of tumor cells. | |||||||||||||||||||||
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References
Keywords
