368434-98-4
Chemical Structure
PCSK9-IN-10
- CAS No.: 368434-98-4
- Formula:C18H23N5O4
- Molecular Weight:373.41
IUPAC Name: 7-(3-methoxybenzyl)-8-((2-methoxyethyl)amino)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
InChIKey: YUNMPASCLGGSKE-UHFFFAOYSA-N
SMILES: O=C(N1C)N(C)C2=C(N(CC3=CC=CC(OC)=C3)C(NCCOC)=N2)C1=O
Biological Activity: PCSK9-IN-10 is a potent and orally active PCSK9 inhibitor with an IC50 value of 6.4 µM. PCSK9-IN-10 increases the expression of LDLR protein and decreases the expression of PCSK9. PCSK9-IN-10 reduces atherosclerosis progression. PCSK9-IN-10 has the potential for the research of hyperlipidemia[1].
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PCSK9-IN-10 | 98.89% | PCSK9-IN-10 is a potent and orally active PCSK9 inhibitor with an IC50 value of 6.4 µM. PCSK9-IN-10 increases the expression of LDLR protein and decreases the expression of PCSK9. PCSK9-IN-10 reduces atherosclerosis progression. PCSK9-IN-10 has the potential for the research of hyperlipidemia. | ||||||||||||||||||||
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Keywords
