36981-91-6
36981-91-6
Chemical Structure
Fepradinol
- CAS No.: 36981-91-6
- Formula:C12H19NO2
- Molecular Weight:209.28
IUPAC Name: 2-((2-hydroxy-2-phenylethyl)amino)-2-methylpropan-1-ol
InChIKey: PVOOBRUZWPQOER-UHFFFAOYSA-N
SMILES: OC(CNC(C)(C)CO)C1=CC=CC=C1
Biological Activity: Fepradinol is an orally active non-steroidal anti-inflammatory compound that alleviates inflammatory responses by stabilizing vascular walls, inhibiting increased vascular permeability, and suppressing leukocyte migration, independent of the cyclooxygenase or prostaglandin synthesis pathways. Fepradinol can be used in studies of acute inflammation, contact dermatitis, and minor sports injuries[1][2].
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Fepradinol | Fepradinol is an orally active non-steroidal anti-inflammatory compound that alleviates inflammatory responses by stabilizing vascular walls, inhibiting increased vascular permeability, and suppressing leukocyte migration, independent of the cyclooxygenase or prostaglandin synthesis pathways. Fepradinol can be used in studies of acute inflammation, contact dermatitis, and minor sports injuries. | |||||||||||||||||||||
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References
- [1]. Masso JM, et al. Effects of fepradinol on rat acute models of vascular permeability and leucocyte migration. Agents and actions. 1994 Oct;42(3-4):118-22.
- [2]. Masso JM, et al. Effect of fepradinol on rat hind paw oedema induced by several inflammatory agents. The Journal of pharmacy and pharmacology. 1993 Nov;45(11):959-62.
