3800-86-0
Chemical Structure
Dexamethasone hemisuccinate
- CAS No.: 3800-86-0
- Formula:C26H33FO8
- Molecular Weight:492.53
IUPAC Name: 4-(2-((8S,9S,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethoxy)-4-oxobutanoic acid
InChIKey: IEKLVCVEJCEIJD-VVOKHRGISA-N
SMILES: O=C1C=C[C@]2(C(CC[C@@]3([C@]2([C@H](C[C@]4([C@]3(C[C@@H]([C@@]4(C(COC(CCC(O)=O)=O)=O)O)C)[H])C)O)F)[H])=C1)C
Biological Activity: Dexamethasone hemisuccinate is a glucocorticoid prodrug and an inhibitor of IL-6 release, and its liposomal formulation is internalized by retinal pigment epithelial cells. Dexamethasone hemisuccinate binds to retinal pigment epithelial cells in a time-dependent manner and exhibits no cytotoxicity toward these cells. Dexamethasone hemisuccinate can be used in research on age-related macular degeneration[1].
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Dexamethasone hemisuccinate | Dexamethasone hemisuccinate is a glucocorticoid prodrug and an inhibitor of IL-6 release, and its liposomal formulation is internalized by retinal pigment epithelial cells. Dexamethasone hemisuccinate binds to retinal pigment epithelial cells in a time-dependent manner and exhibits no cytotoxicity toward these cells. Dexamethasone hemisuccinate can be used in research on age-related macular degeneration. | |||||||||||||||||||||
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