38275-34-2
38275-34-2
Chemical Structure
PK11000
- CAS No.: 38275-34-2
- Formula:C6H5ClN2O4S
- Molecular Weight:236.63
IUPAC Name: 5-chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid
InChIKey: WZUPWJVRWIVWEF-UHFFFAOYSA-N
SMILES: O=C(C1=NC(S(=O)(C)=O)=NC=C1Cl)O
Biological Activity: PK11000 is an alkylating agent, and stabilizes the DNA-binding domain of both WT and mutant p53 proteins by covalent cysteine modification without compromising DNA binding. PK11000 has anti-tumor activities[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PK11000 | 99.56% | PK11000 is an alkylating agent, and stabilizes the DNA-binding domain of both WT and mutant p53 proteins by covalent cysteine modification without compromising DNA binding. PK11000 has anti-tumor activities. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.71
HY-W003098R4,6-Dimethyl-2-methylsulfonylpyrimidine (Standard) -
Similarity Score 0.71
HY-W018749Clopyralid -
Similarity Score 0.69
HY-W0073985,6-Dichloronicotinic acid -
Similarity Score 0.69
HY-W0025534,6-Dichloronicotinic acid -
Similarity Score 0.69
HY-W354583Clopyralid(2-hydroxyethyl)ammonium -
Similarity Score 0.69
HY-691422-Chloropyrimidine-5-carboxylic acid -
Similarity Score 0.69
HY-W0456814-Chloropyridine-2,6-dicarboxylic acid -
Similarity Score 0.69
HY-W0059836-Chloropyrimidine-4-carboxylic acid -
Similarity Score 0.68
HY-W008484Aminopyralid -
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