38275-34-2
Chemical Structure
PK11000
- CAS No.: 38275-34-2
- Formula:C6H5ClN2O4S
- Molecular Weight:236.63
IUPAC Name: 5-chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid
InChIKey: WZUPWJVRWIVWEF-UHFFFAOYSA-N
SMILES: O=C(C1=NC(S(=O)(C)=O)=NC=C1Cl)O
Biological Activity: PK11000 is an alkylating agent, and stabilizes the DNA-binding domain of both WT and mutant p53 proteins by covalent cysteine modification without compromising DNA binding. PK11000 has anti-tumor activities[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PK11000 | 99.56% | PK11000 is an alkylating agent, and stabilizes the DNA-binding domain of both WT and mutant p53 proteins by covalent cysteine modification without compromising DNA binding. PK11000 has anti-tumor activities. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords