38970-49-9
Chemical Structure
Tschimganin
- CAS No.: 38970-49-9
- Formula:C18H24O4
- Molecular Weight:304.38
InChIKey: KTOAGBIQQPGNIR-MRAWALMUSA-N
SMILES: C[C@](C1(C)C)(CC[C@]1([H])C2)[C@H]2OC(C(C=C3)=CC(OC)=C3O)=O
Biological Activity: Tschimganin is an orally active monoterpene benzoate natural product with antibacterial and other activities. Tschimganin reverses the drug resistance of Staphylococcus aureus and exerts antibacterial, membrane-disrupting, biofilm-inhibiting, and anti-inflammatory effects. Tschimganin acts as an Estrogen Receptor agonist, increases uterine mass and water content and affects ovarian mass in juvenile rats. Tschimganin is useful for research on bacterial infections and also serves as an intermediate for research on organic synthesis[1][2][3][4][5].
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Tschimganin | Tschimganin is an orally active monoterpene benzoate natural product with antibacterial and other activities. Tschimganin reverses the drug resistance of Staphylococcus aureus and exerts antibacterial, membrane-disrupting, biofilm-inhibiting, and anti-inflammatory effects. Tschimganin acts as an Estrogen Receptor agonist, increases uterine mass and water content and affects ovarian mass in juvenile rats. Tschimganin is useful for research on bacterial infections and also serves as an intermediate for research on organic synthesis. | |||||||||||||||||||||
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References
- [1]. Zhou Y, et al. Synthesis, Insecticidal, Fungicidal Activities and Structure⁻Activity Relationships of Tschimganin Analogs. Molecules (Basel, Switzerland). 2018 Jun 18;23(6):1473.
- [2]. Nazrullaev SS, et al. Estrogen activity of terpenoids from plants of the genus Ferula. Chemistry of natural compounds. 2008 Sep;44(5):572-7.
- [3]. Liu C, et al. Design, synthesis, and insecticidal activity of novel terpenoid ester compounds containing bicyclo [2.2. 1] heptane against Aphis gossypii Glover. Advanced Agrochem. 2024 Jun 1;3(2):171-81.
- [4]. Alqahtani OS, et al. Integrated Phytochemical Exploration Studies and Computational Biology Approaches of Aloe Vera (L.) Burm. f., Flowers Coupled with Human ACE. Journal of Pharmaceutical Innovation. 2026 Apr;21(2):119.
- [5]. Trusheva B, et al. Antibacterial mono- and sesquiterpene esters of benzoic acids from Iranian propolis. Chemistry Central journal. 2010 Mar 29;4:8.
