39236-46-9
39236-46-9
Chemical Structure
Imidazolidinyl urea
- CAS No.: 39236-46-9
- Formula:C11H16N8O8
- Molecular Weight:388.29
IUPAC Name: 1,1'-methylenebis(3-(3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)urea)
InChIKey: ZCTXEAQXZGPWFG-UHFFFAOYSA-N
SMILES: O=C(NC(C(N1)=O)N(CO)C1=O)NCNC(NC(C(N2)=O)N(CO)C2=O)=O
Biological Activity: Imidazolidinyl urea is a commonly used antibacterial preservative in cosmetics and pharmaceuticals that releases formaldehyde through decomposition. Imidazolidinyl urea can also be used in the preparation of multifunctional hydrogels for the care of infectious wounds. Imidazolidinyl urea has broad-spectrum antibacterial activity, which mainly inhibits the reproduction of gram-negative bacteria and gram-positive bacteria, and restricts the growth of yeast and mold to a certain extent. Imidazolidinyl urea can induce non-histaminergic allergy by MRGPRX2 activation of mast cells[1][2][3].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Imidazolidinyl urea | 99.99% | Imidazolidinyl urea is a commonly used antibacterial preservative in cosmetics and pharmaceuticals that releases formaldehyde through decomposition. Imidazolidinyl urea can also be used in the preparation of multifunctional hydrogels for the care of infectious wounds. Imidazolidinyl urea has broad-spectrum antibacterial activity, which mainly inhibits the reproduction of gram-negative bacteria and gram-positive bacteria, and restricts the growth of yeast and mold to a certain extent. Imidazolidinyl urea can induce non-histaminergic allergy by MRGPRX2 activation of mast cells. | ||||||||||||||||||||
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Imidazolidinyl urea (Standard) | ≥98% | Imidazolidinyl urea (Standard) is the analytical standard of Imidazolidinyl urea. This product is intended for research and analytical applications. Imidazolidinyl urea is a commonly used antibacterial preservative in cosmetics and pharmaceuticals that releases formaldehyde through decomposition. Imidazolidinyl urea can also be used in the preparation of multifunctional hydrogels for the care of infectious wounds. Imidazolidinyl urea has broad-spectrum antibacterial activity, which mainly inhibits the reproduction of gram-negative bacteria and gram-positive bacteria, and restricts the growth of yeast and mold to a certain extent. Imidazolidinyl urea can induce non-histaminergic allergy by MRGPRX2 activation of mast cells. | ||||||||||||||||||||
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(S)-Allantoin | (S)-Allantoin is the S-isomer of Allantoin (HY-N0543). (S)-Allantoin binds selectively in the active site of urate oxidase. (S)-Allantoin can be converted to Allantoate by the action of allantoicase. (S)-Allantoin serves as a source of nitrogen in Arabidopsis thaliana. | |||||||||||||||||||||
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Imuracetam | Imuracetam is a racetam compound. Racetam compounds have good cognitive-enhancing effects. | |||||||||||||||||||||
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ICRF 192 | ICRF 192 is a weak DNA topoisomerase II (DNA topoisomerase II) inhibitor with an IC50 of 91 μM. ICRF 192 forms an iron-chelating derivative via ring-opening hydrolysis, which can displace Fe3+ from the Fe3+-doxorubicin complex. ICRF 192 is used for studies on the structure-activity relationship of bisdioxopiperazines and the cardiotoxicity of anthracycline drugs. | |||||||||||||||||||||
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Dexrazoxane hydrochloride | 99.83% | Dexrazoxane hydrochloride (ICRF-187 hydrochloride) is a heart protectant that can help preserve ovarian function and fertility. Dexrazoxane hydrochloride has antioxidant and anti-inflammatory properties, can cross the blood-brain barrier, improves motor function disorders, and offers neuroprotective effects, making it useful in the study of neurodegenerative diseases. | ||||||||||||||||||||
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Allantoin (Standard) | 98.87% | Allantoin (Standard) is the analytical standard of Allantoin. This product is intended for research and analytical applications. Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth. | ||||||||||||||||||||
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Allantoin-13C2,15N4 | 99.90% | Allantoin-13C2,15N4 is the 13C and 15N labeled Allantoin. Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth. | ||||||||||||||||||||
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Allantoin, (-)- | Allantoin, (-)- is a natural product that can be isolated from animals, plants and bacteria. | |||||||||||||||||||||
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Cyclopetide 1 | Cyclopetide 1 (Compound 1) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 25 μg/mL. | |||||||||||||||||||||
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Diazolidinyl urea | 95.0% | Diazolidinyl urea is a broad-spectrum preservative commonly used in cosmetics. Diazolidinyl urea exerts antibacterial effects by decomposing and releasing formaldehyde. Diazolidinyl urea is effective against most contaminating microorganisms, especially Pseudomonas. | ||||||||||||||||||||
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Maleimide-NOTA | 99.26% | Maleimide-NOTA is a chelate. Maleimide-NOTA can be site-specifically coupled to the hPD-L1 nanobody bearing the Cys-tag. Maleimide-NOTA can specifically conjugate to A20FMDV2 (HY-P1654). The [68Ga]Ac-CG6 formed by the conjugation of 68Ga radiolabeled Maleimide-NOTA with A20FMDV2 can be used for PET imaging of αvβ6 integrin-positive pancreatic ductal adenocarcinoma. | ||||||||||||||||||||
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References
- [1]. Gao J, et al. Imidazolidinyl urea activates mast cells via MRGPRX2 to induce non-histaminergic allergy. Toxicol Res (Camb). 2021 Apr 29;10(3):467-475. [Content Brief]
- [2]. Doi T, et al. Characterization of the decomposition of compounds derived from imidazolidinyl urea in cosmetics and patch test materials. Contact Dermatitis. 2012 Nov;67(5):284-92. [Content Brief]
- [3]. Wu Q, et al. On-demand imidazolidinyl urea-based tissue-like, self-healable, and antibacterial hydrogels for infectious wound care. Bioact Mater. 2024 Oct 15;44:116-130. [Content Brief]
