396073-89-5
Chemical Structure
BN82002
- CAS. Nr.: 396073-89-5
- Formula:C19H25N3O4
- Molecular Weight:359.42
IUPAC Name: 4-(dimethylamino)-2-methoxy-6-((methyl(4-nitrophenethyl)amino)methyl)phenol
InChIKey: GOKYHQGRIIXMNE-UHFFFAOYSA-N
SMILES: OC1=C(CN(C)CCC2=CC=C([N+]([O-])=O)C=C2)C=C(N(C)C)C=C1OC
Biological Activity: BN82002 is a potent, selective and irreversible inhibitor of CDC25 phosphatase family. BN82002 inhibits CDC25A, CDC25B2, CDC25B3, CDC25C CDC25A, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 µM, respectively. BN82002 displays ~20-fold greater selectivity over CD45 tyrosine phosphatase[1].
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BN82002 | BN82002 is a potent, selective and irreversible inhibitor of CDC25 phosphatase family. BN82002 inhibits CDC25A, CDC25B2, CDC25B3, CDC25C CDC25A, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 µM, respectively. BN82002 displays ~20-fold greater selectivity over CD45 tyrosine phosphatase. | |||||||||||||||||||||
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Keywords
