40456-51-7
40456-51-7
Chemical Structure
Bursehernin
Synonym(s): Methylpluviatolide
- CAS. Nr.: 40456-51-7
- Formula:C21H22O6
- Molecular Weight:370.40
IUPAC Name: (3R,4R)-4-(benzo[d][1,3]dioxol-5-ylmethyl)-3-(3,4-dimethoxybenzyl)dihydrofuran-2(3H)-one
InChIKey: IYBDDRJHJMFFBB-JKSUJKDBSA-N
SMILES: O=C1OC[C@H](CC2=CC=C(OCO3)C3=C2)[C@H]1CC4=CC(OC)=C(C=C4)OC
Biological Activity: Bursehernin (Methylpluviatolide) is an antitumor agent. Bursehernin induces Apoptosis and cell cycle arrest at G2/M phase. Bursehernin shows anti-proliferative activity[1][2].
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Bursehernin | Bursehernin (Methylpluviatolide) is an antitumor agent. Bursehernin induces Apoptosis and cell cycle arrest at G2/M phase. Bursehernin shows anti-proliferative activity. | |||||||||||||||||||||
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References
- [1]. Rattanaburee T, et al. Anticancer activity of synthetic (±)-kusunokinin and its derivative (±)-bursehernin on human cancer cell lines. Biomed Pharmacother. 2019 Sep;117:109115. [Content Brief]
- [2]. McDoniel PB, et al. Antitumor activity of Bursera schlechtendalii (burseraceae): isolation and structure determination of two new lignans. J Pharm Sci. 1972 Dec;61(12):1992-4. [Content Brief]
Keywords
