404886-32-4
Chemical Structure
Fosbretabulin tromethamine
- CAS No.: 404886-32-4
- Formula:C22H32NO11P
- Molecular Weight:517.46
IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol (Z)-2-methoxy-5-(3,4,5-trimethoxystyryl)phenyl phosphate
InChIKey: FIDMEHCRMLKKPZ-YSMBQZINSA-N
SMILES: OCC(CO)(N)CO.O=P(O)(O)OC1=C(C=CC(/C=C\C2=CC(OC)=C(C(OC)=C2)OC)=C1)OC
Biological Activity: Fosbretabulin (tromethamine), also known as combretastatin A4 phosphate (CA4P), is a vascular disrupting agent evaluated for its efficacy against anaplastic thyroid carcinoma (ATC). It targets tumor neovasculature, causing acute and reversible reductions in tumor blood flow and central necrosis[1].
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Fosbretabulin tromethamine | Fosbretabulin (tromethamine), also known as combretastatin A4 phosphate (CA4P), is a vascular disrupting agent evaluated for its efficacy against anaplastic thyroid carcinoma (ATC). It targets tumor neovasculature, causing acute and reversible reductions in tumor blood flow and central necrosis. | |||||||||||||||||||||
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Keywords
