Fosbretabulin tromethamine
Fosbretabulin (tromethamine), also known as combretastatin A4 phosphate (CA4P), is a vascular disrupting agent evaluated for its efficacy against anaplastic thyroid carcinoma (ATC). It targets tumor neovasculature, causing acute and reversible reductions in tumor blood flow and central necrosis.
For research use only. We do not sell to patients.
- CAS No.: 404886-32-4
- Formula: C22H32NO11P
- Molecular Weight:517.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 404886-32-4
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Molecular Weight 517.46
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Formula C22H32NO11P
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SMILES
OCC(CO)(N)CO.O=P(O)(O)OC1=C(C=CC(/C=C\C2=CC(OC)=C(C(OC)=C2)OC)=C1)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)