4150-30-5
Chemical Structure
5-Androstenetriol
- CAS No.: 4150-30-5
- Formula:C19H30O3
- Molecular Weight:306.44
IUPAC Name: (3S,8R,9S,10R,13S,14S,16R,17R)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,16,17-triol
InChIKey: GUGSXATYPSGVAY-DHKQUUGRSA-N
SMILES: C[C@@]12[C@@H](O)[C@H](O)C[C@@]1([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC2
Biological Activity: 5-Androstenetriol is a systemic radiation protector that can boost the host's immunity, leading to increased resistance to infections. 5-Androstenetriol can raise levels of IL-2, IL-3, and IFN, while countering the immunosuppressive effects of Hydrocortisone (HY-N0583)[1][2].
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5-Androstenetriol | 5-Androstenetriol is a systemic radiation protector that can boost the host's immunity, leading to increased resistance to infections. 5-Androstenetriol can raise levels of IL-2, IL-3, and IFN, while countering the immunosuppressive effects of Hydrocortisone (HY-N0583). | |||||||||||||||||||||
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- [1]. R M Loria, et al. Androstenetriol and androstenediol. Protection against lethal radiation and restoration of immunity after radiation injury. Ann N Y Acad Sci. 2000:917:860-7. [Content Brief]
- [2]. Mark H Whitnall, et al. Molecular specificity of 5-androstenediol as a systemic radioprotectant in mice. Immunopharmacol Immunotoxicol. 2005;27(1):15-32. [Content Brief]
Keywords
