41708-72-9
41708-72-9
Chemical Structure
Tocainide
- CAS No.: 41708-72-9
- Formula:C11H16N2O
- Molecular Weight:192.26
IUPAC Name: 2-amino-N-(2,6-dimethylphenyl)propanamide
InChIKey: BUJAGSGYPOAWEI-UHFFFAOYSA-N
SMILES: CC(N)C(NC1=C(C)C=CC=C1C)=O
Biological Activity: Tocainide hydrochloride is an orally activesodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus[1][2].
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Tocainide | 99.06% | Tocainide hydrochloride is an orally activesodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus. | ||||||||||||||||||||
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Tocainide (Standard) | ≥98% | Tocainide (Standard) is the analytical standard of Tocainide. This product is intended for research and analytical applications. Tocainide hydrochloride is an orally activesodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.97
HY-B1798ATocainide hydrochloride -
Similarity Score 0.85
HY-W357818Glycinexylidide -
Similarity Score 0.84
HY-44009Lidocaine impurity 1 -
Similarity Score 0.82
HY-W0779042-Chloro-N-(2,6-dimethylphenyl)acetamide -
Similarity Score 0.81
HY-145482RW36017 (Standard) -
Similarity Score 0.81
HY-118167Monoethylglycinexylidide -
Similarity Score 0.80
HY-Z6958RPrilocaine impurity 1 (Standard) -
Similarity Score 0.80
HY-W1007842,6-Dimethylphenylthiourea -
Similarity Score 0.79
HY-W1977132-Amino-N-phenylpropanamide hydrochloride -
Explore the MedChemAI to find more analogs
References
- [1]. Alpert JS, et al. Chemistry, pharmacology, antiarrhythmic efficacy and adverse effects of tocainide hydrochloride, an orally active structural analog of lidocaine. Pharmacotherapy. 1983 Nov-Dec;3(6):316-23. [Content Brief]
- [2]. De Luca A,et al.Optimal requirements for high affinity and use-dependent block of skeletal muscle sodium channel by N-benzyl analogs of tocainide-like compounds.Mol Pharmacol. 2003 Oct;64(4):932-45. [Content Brief]
