41708-72-9
41708-72-9
Chemical Structure
Tocainide
- CAS No.: 41708-72-9
- Formula:C11H16N2O
- Molecular Weight:192.26
IUPAC Name: 2-amino-N-(2,6-dimethylphenyl)propanamide
InChIKey: BUJAGSGYPOAWEI-UHFFFAOYSA-N
SMILES: CC(N)C(NC1=C(C)C=CC=C1C)=O
Biological Activity: Tocainide hydrochloride is an orally activesodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tocainide | 99.06% | Tocainide hydrochloride is an orally activesodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus. | ||||||||||||||||||||
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Tocainide (Standard) | ≥98% | Tocainide (Standard) is the analytical standard of Tocainide. This product is intended for research and analytical applications. Tocainide hydrochloride is an orally activesodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus. | ||||||||||||||||||||
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Monoethylglycinexylidide | 99.69% | Monoethylglycinexylidide (MEGX; Norlidocaine) is the major metabolite of Lidocaine (HY-B0185), produced via oxidative metabolism by cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide can be used for research on liver cirrhosis. | ||||||||||||||||||||
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Xylopropamine hydrobromide | Xylopropamine hydrobromide is an analgesic compound. | |||||||||||||||||||||
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W36017 (Standard) | ≥98% | 8-Hydroxyquinoline (hemisulfate) (Standard) is the analytical standard of 8-Hydroxyquinoline (hemisulfate). This product is intended for research and analytical applications. 8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor. | ||||||||||||||||||||
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Lidocaine impurity 1 | 99.92% | Lidocaine impurity 1 is an impurity of Lidocaine (HY-B0185). | ||||||||||||||||||||
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Tocainide hydrochloride | 98.63% | Tocainide hydrochloride is a sodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus. | ||||||||||||||||||||
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2-Chloro-N-(2,6-dimethylphenyl)acetamide | 2-Chloro-N-(2,6-dimethylphenyl) acetamide is a cyclooxygenase (COX) inhibitor predicted by molecular topology. | |||||||||||||||||||||
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2,6-Dimethylphenylthiourea | 99.81% | 2,6-Dimethylphenylthiourea is a Xylazine metabolite. Xylazine is the first and most widely used α2-agonist. | ||||||||||||||||||||
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2-Amino-N-phenylpropanamide hydrochloride | 2-Amino-N-phenylpropanamide (Compound 5b) hydrochloride is a Tocainid (HY-B1798) analog. Tocainid is an antiarrythmic agent. | |||||||||||||||||||||
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Glycinexylidide | 95.06% | Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local agent that can suppress or relieve pain, that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease. | ||||||||||||||||||||
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Prilocaine impurity 1 (Standard) | ≥98% | 2-Bromo-N-(o-tolyl)propanamide (Prilocaine Impurity) (Standard) is the analytical standard of 2-Bromo-N-(o-tolyl)propanamide (Prilocaine Impurity). This product is intended for research and analytical applications. | ||||||||||||||||||||
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References
- [1]. Alpert JS, et al. Chemistry, pharmacology, antiarrhythmic efficacy and adverse effects of tocainide hydrochloride, an orally active structural analog of lidocaine. Pharmacotherapy. 1983 Nov-Dec;3(6):316-23. [Content Brief]
- [2]. De Luca A,et al.Optimal requirements for high affinity and use-dependent block of skeletal muscle sodium channel by N-benzyl analogs of tocainide-like compounds.Mol Pharmacol. 2003 Oct;64(4):932-45. [Content Brief]
