1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. Tocainide hydrochloride

Tocainide hydrochloride 

Cat. No.: HY-B1798A Purity: >98.0%
Handling Instructions

Tocainide hydrochloride is a sodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus.

For research use only. We do not sell to patients.

Tocainide hydrochloride Chemical Structure

Tocainide hydrochloride Chemical Structure

CAS No. : 71395-14-7

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Tocainide hydrochloride is a sodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus[1][2].

IC50 & Target

IC50: sodium channel[1]

In Vivo

Tocainide (100 mg/kg) effectively suppresses ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Termination of tocainide infusion in both digitalis toxicity and coronary occlusion models results in prompt return of ventricular ectopic activity[1].

Molecular Weight

228.72

Formula

C₁₁H₁₇ClN₂O

CAS No.

71395-14-7

SMILES

CC(N)C(NC1=C(C)C=CC=C1C)=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under argon

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under argon)

References

Purity: >98.0%

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Keywords:

TocainideSodium ChannelNa channelsNa+ channelsamineanalog,tinnitusInhibitorinhibitorinhibit

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Tocainide hydrochloride
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HY-B1798A
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