41729-52-6
41729-52-6
Chemical Structure
Dezaguanine
- CAS No.: 41729-52-6
- Formula:C6H6N4O
- Molecular Weight:150.14
IUPAC Name: 6-amino-1,5-dihydro-4H-imidazo[4,5-c]pyridin-4-one
InChIKey: KXBCLNRMQPRVTP-UHFFFAOYSA-N
SMILES: O=C1NC(N)=CC=2NC=NC12
Biological Activity: Dezaguanine is a purine analog. Dezaguanine exhibits antitumor activity in leukemia and breast cancer cells. Dezaguanine can be used in cancer-related research[1][2].
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Dezaguanine | Dezaguanine is a purine analog. Dezaguanine exhibits antitumor activity in leukemia and breast cancer cells. Dezaguanine can be used in cancer-related research. | |||||||||||||||||||||
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References
- [1]. Schneller S W, et al. Synthesis and biological evaluation of 6-amino-1H-pyrrolo [3, 2-c] pyridin-4 (5H)-one (3, 7-dideazaguanine). Journal of medicinal chemistry, 1984, 27(12): 1737-1739.
- [2]. Margolin K, et al. 3-Deazaguanine: report of a phase I trial and drug-related cardiac toxicity. Invest New Drugs. 1990;8(4):369-376. [Content Brief]
