421586-94-9
421586-94-9
Chemical Structure
8012–3246
- CAS No.: 421586-94-9
- Formula:C18H13N5O3
- Molecular Weight:347.33
InChIKey: GSYJLNZKXBTEBE-UHFFFAOYSA-N
SMILES: NC1=C(C#N)C(C(C(C2=CC=NC=C2)=NN3)=C3O1)C4=CC=C(O)C(O)=C4
Biological Activity: 8012-3246 is a selective PLK2 inhibitor with an IC50 of 774.5 nM. 8012-3246 suppresses GSK3β phosphorylation. 8012-3246 exhibits potent anticancer activity against colorectal cancer[1].
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8012–3246 | 99.72% | 8012-3246 is a selective PLK2 inhibitor with an IC50 of 774.5 nM. 8012-3246 suppresses GSK3β phosphorylation. 8012-3246 exhibits potent anticancer activity against colorectal cancer. | ||||||||||||||||||||
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References
Keywords
