4263-87-0
Chemical Structure
Dehydrodiconiferyl alcohol
- CAS No.: 4263-87-0
- Formula:C20H22O6
- Molecular Weight:358.39
IUPAC Name: (E)-4-(3-(hydroxymethyl)-5-(3-hydroxyprop-1-en-1-yl)-7-methoxy-2,3-dihydrobenzofuran-2-yl)-2-methoxyphenol
InChIKey: KUSXBOZNRPQEON-ONEGZZNKSA-N
SMILES: OC1=CC=C(C2OC3=C(C2CO)C=C(/C=C/CO)C=C3OC)C=C1OC
Biological Activity: Dehydrodiconiferyl alcohol is an estrogen receptor agonist that can promote BMP-2-induced osteoblastogenesis. Dehydrodiconiferyl alcohol also exerts anti-inflammatory activity through inactivation of NF-κB pathways[1][2].
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Dehydrodiconiferyl alcohol | 98.32% | Dehydrodiconiferyl alcohol is an estrogen receptor agonist that can promote BMP-2-induced osteoblastogenesis. Dehydrodiconiferyl alcohol also exerts anti-inflammatory activity through inactivation of NF-κB pathways. | ||||||||||||||||||||
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- [1]. Lee W, et, al. Dehydrodiconiferyl alcohol promotes BMP-2-induced osteoblastogenesis through its agonistic effects on estrogen receptor. Biochem Biophys Res Commun. 2018 Jan 15;495(3):2242-2248. [Content Brief]
- [2]. Hu X, et, al. Dehydrodiconiferyl alcohol from Silybum marianum (L.) Gaertn accelerates wound healing via inactivating NF-κB pathways in macrophages. J Pharm Pharmacol. 2020 Feb;72(2):305-317. [Content Brief]
Keywords