432018-03-6
432018-03-6
Chemical Structure
CCC-0975
- CAS No.: 432018-03-6
- Formula:C21H17ClF3N3O3S
- Molecular Weight:483.89
IUPAC Name: 2-(N-(2-chloro-5-(trifluoromethyl)phenyl)phenylsulfonamido)-N-(pyridin-4-ylmethyl)acetamide
InChIKey: JKZSHWDPOQYSJW-UHFFFAOYSA-N
SMILES: O=C(CN(S(=O)(C1=CC=CC=C1)=O)C2=CC(C(F)(F)F)=CC=C2Cl)NCC3=CC=NC=C3
Biological Activity: CCC-0975 is a hepatitis B virus (HBV) inhibitor (EC50=10 μM). CCC-0975 interferes with the conversion of relaxed circular DNA (rcDNA) to cccDNA, synchronously reducing cccDNA and its precursor deproteinized rcDNA (DP-rcDNA) without promoting their intracellular degradation. CCC-0975 is promising for research of chronic hepatitis B[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CCC-0975 | 99.49% | CCC-0975 is a hepatitis B virus (HBV) inhibitor (EC50=10 μM). CCC-0975 interferes with the conversion of relaxed circular DNA (rcDNA) to cccDNA, synchronously reducing cccDNA and its precursor deproteinized rcDNA (DP-rcDNA) without promoting their intracellular degradation. CCC-0975 is promising for research of chronic hepatitis B. | ||||||||||||||||||||
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