443790-30-5
443790-30-5
Chemical Structure
COX-2/15-LOX-IN-5
- CAS No.: 443790-30-5
- Formula:C25H21N3O3S
- Molecular Weight:443.52
InChIKey: KDHSBBNEBXGUJI-JWGURIENSA-N
SMILES: COC1=CC=C(C=C1)NC(CSC2=N/C(C(N2C3=CC=CC=C3)=O)=C\C4=CC=CC=C4)=O
Biological Activity: COX-2/15-LOX-IN-5 (Compound 4f) is a dual inhibitor of COX-2/15-LOX. COX-2/15-LOX-IN-5 attenuates increased NF-κB activation in RAW 264.7 macrophages mediated by lipopolysaccharide (HY-D1056). COX-2/15-LOX-IN-5 has anti-inflammatory and antioxidant activities[1].
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COX-2/15-LOX-IN-5 | COX-2/15-LOX-IN-5 (Compound 4f) is a dual inhibitor of COX-2/15-LOX. COX-2/15-LOX-IN-5 attenuates increased NF-κB activation in RAW 264.7 macrophages mediated by lipopolysaccharide (HY-D1056). COX-2/15-LOX-IN-5 has anti-inflammatory and antioxidant activities. | |||||||||||||||||||||
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