447415-34-1
447415-34-1
Chemical Structure
GC 14
- CAS. Nr.: 447415-34-1
- Formula:C26H27NO6
- Molecular Weight:449.50
IUPAC Name: 2-(4-((6-hydroxy-5-isopropyl-4'-nitro-[1,1'-biphenyl]-3-yl)methyl)-3,5-dimethylphenoxy)acetic acid
InChIKey: PBZAEAFSLYJVGD-UHFFFAOYSA-N
SMILES: O=C(O)COC1=CC(C)=C(CC2=CC(C3=CC=C([N+]([O-])=O)C=C3)=C(O)C(C(C)C)=C2)C(C)=C1
Biological Activity: GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 35 nM and 200 nM for hTRβ and hTRα, respectively.
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GC 14 | GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 35 nM and 200 nM for hTRβ and hTRα, respectively. | |||||||||||||||||||||
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