457939-22-9
457939-22-9
Chemical Structure
CR-3294
- CAS No.: 457939-22-9
- Formula:C14H22N4S
- Molecular Weight:278.42
IUPAC Name: N-(4-(3-pentylthioureido)phenyl)acetimidamide
InChIKey: HIIQJRQLPZAVFN-UHFFFAOYSA-N
SMILES: CC(NC1=CC=C(NC(NCCCCC)=S)C=C1)=N
Biological Activity: CR-3294 is an autophagy inducer in hypoxic cells. CR-3294 is an inducible enzyme nitric oxide synthase (iNOS) inhibitor. CR-3294 inhibits both the DNA binding of HIF-1alpha and VEGF mRNA synthesis. CR-3294 can be used for the study of breast cancer and inflammatory bowel disease (IBD), such as Crohn’s disease, ulcerative colitis[1].
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CR-3294 | CR-3294 is an autophagy inducer in hypoxic cells. CR-3294 is an inducible enzyme nitric oxide synthase (iNOS) inhibitor. CR-3294 inhibits both the DNA binding of HIF-1alpha and VEGF mRNA synthesis. CR-3294 can be used for the study of breast cancer and inflammatory bowel disease (IBD), such as Crohn’s disease, ulcerative colitis. | |||||||||||||||||||||
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References
Keywords
