482598-46-9
Chemical Structure
Δ7(Z)-C14-HSL
Synonym(s): N-(3-Oxo-7Z-tetradecenoyl)-L-homoserine lactone
- CAS No.: 482598-46-9
- Formula:C18H29NO4
- Molecular Weight:323.43
IUPAC Name: N-((2S,3R,E)-3-hydroxy-1-(((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octadec-4-en-2-yl)-12-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)dodecanamide
InChIKey: MGGGOCSKDLGISA-PTZVLDCSSA-N
SMILES: CCCCCC/C=C\CCCC(CC(N[C@@H]1C(OCC1)=O)=O)=O
Biological Activity: Δ7(Z)-C14-HSL (Compound 12) is an immunosuppressive agent that can inhibit the proliferation of mouse splenic cells with an IC50 of 17 μM. Δ7(Z)-C14-HSL can be used for further studying its potential as a molecular mechanism in TNF-R-driven immune diseases, especially autoimmune diseases such as psoriasis, rheumatoid arthritis, and type 1 diabetes[1].
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Δ7(Z)-C14-HSL | Δ7(Z)-C14-HSL (Compound 12) is an immunosuppressive agent that can inhibit the proliferation of mouse splenic cells with an IC50 of 17 μM. Δ7(Z)-C14-HSL can be used for further studying its potential as a molecular mechanism in TNF-R-driven immune diseases, especially autoimmune diseases such as psoriasis, rheumatoid arthritis, and type 1 diabetes. | |||||||||||||||||||||
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