499149-94-9
499149-94-9
Chemical Structure
EP3 antagonist 6
- CAS No.: 499149-94-9
- Formula:C31H37NO4
- Molecular Weight:487.63
InChIKey: PUQCPIMXFYPCIE-MUUNZHRXSA-N
SMILES: CC(C)C[C@H](C1=CC(C)=CC(C)=C1)NC(C2=C(C=CC(COC3=C(C=CC=C3)C)=C2)CCC(O)=O)=O
Biological Activity: EP3 antagonist 6 (compound 5) is a potent, orally and selective EP3 receptor antagonist, with an IC50 of 1.9 nM. EP3 antagonist 6 can inhibits PGE2-induced (HY-101952) uterine contraction in pregnant rats[1].
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EP3 antagonist 6 | EP3 antagonist 6 (compound 5) is a potent, orally and selective EP3 receptor antagonist, with an IC50 of 1.9 nM. EP3 antagonist 6 can inhibits PGE2-induced (HY-101952) uterine contraction in pregnant rats. | |||||||||||||||||||||
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References
Keywords
