50270-33-2
Chemical Structure
Isofezolac
- CAS No.: 50270-33-2
- Formula:C23H18N2O2
- Molecular Weight:354.40
IUPAC Name: 2-(1,3,4-triphenyl-1H-pyrazol-5-yl)acetic acid
InChIKey: LZRDDINFIHUVCX-UHFFFAOYSA-N
SMILES: O=C(CC1=C(C(C2=CC=CC=C2)=NN1C3=CC=CC=C3)C4=CC=CC=C4)O
Biological Activity: Isofezolac (LM 22070) is a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin-synthetase. Isofezolac anti-inflammatory, and antipyretic properties[1][2].
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Isofezolac | Isofezolac (LM 22070) is a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin-synthetase. Isofezolac anti-inflammatory, and antipyretic properties. | |||||||||||||||||||||
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- [1]. J Mizoule, et al. Study of two new non-steroid anti-inflammatory drugs having a pyrazole structure (LM 22070 and LM 22102). Arch Int Pharmacodyn Ther. 1979 Apr;238(2):305-32. [Content Brief]
- [2]. I Rocher, et al. The effect of antacid and aspirin on the bioavailability of isofezolac in man. Int J Clin Pharmacol Ther Toxicol. 1984 Sep;22(9):464-9. [Content Brief]
Keywords