50913-82-1
50913-82-1
Chemical Structure
ORG-2766
- CAS No.: 50913-82-1
- Formula:C40H55N9O11S
- Molecular Weight:869.98
InChIKey: QUCFVNGGGFLOES-ACQYNFKHSA-N
SMILES: O=C(O)[C@H](CC1=CC=CC=C1)NC([C@@H](CCCCN)NC([C@H](CC2=CC=CC=C2)NC([C@H](CC3=CNC=N3)NC([C@H](CCC(O)=O)NC([C@H](CCS(C)(=O)=O)N)=O)=O)=O)=O)=O
Biological Activity: ORG-2766 is an adrenocorticotropic hormone ACTH 4-9 analog and neurotrophic peptide. ORG-2766 affects behavioral processes such as memory and attention in animals, improving symptoms in rats with experimental allergic neuritis. ORG-2766 has a neuroprotective effect[1][2].
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ORG-2766 | ORG-2766 is an adrenocorticotropic hormone ACTH 4-9 analog and neurotrophic peptide. ORG-2766 affects behavioral processes such as memory and attention in animals, improving symptoms in rats with experimental allergic neuritis. ORG-2766 has a neuroprotective effect. | |||||||||||||||||||||
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References
- [1]. Goldman H, et al. Cerebral blood flow after treatment with ORG-2766, a potent analog of ACTH 4--9. Pharmacol Biochem Behav. 1979 Jun;10(6):883-7. [Content Brief]
- [2]. Duckers HJ, et al. The neurotrophic analogue of ACTH(4-9), Org 2766, protects against experimental allergic neuritis. Brain. 1993 Oct;116 ( Pt 5):1059-75. [Content Brief]
