51596-10-2
51596-10-2
Chemical Structure
Milbemycin A3
- CAS No.: 51596-10-2
- Formula:C31H44O7
- Molecular Weight:528.68
InChIKey: ZLBGSRMUSVULIE-GSMJGMFJSA-N
SMILES: C[C@H]1CC[C@@]2(O[C@@H]1C)C[C@@H]3C[C@@H](C/C=C(C)/C[C@@H](C)/C=C/C=C4CO[C@H]5[C@]\4(O)[C@H](C(O3)=O)C=C(C)[C@H]5O)O2
Biological Activity: Milbemycin A3 is a 16-membered macrocyclic lactone compound found in the soil bacterium Saccharopolyspora hygroscopicus subsp. aureolacrimosus. Milbemycin A3 enhances the opening of glutamate- and GABA-gated chloride channels and exhibits insecticidal activity. Milbemycin A3 can be used in insect resistance-related research[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Milbemycin A3 | 99.46% | Milbemycin A3 is a 16-membered macrocyclic lactone compound found in the soil bacterium Saccharopolyspora hygroscopicus subsp. aureolacrimosus. Milbemycin A3 enhances the opening of glutamate- and GABA-gated chloride channels and exhibits insecticidal activity. Milbemycin A3 can be used in insect resistance-related research. | ||||||||||||||||||||
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Milbemycin A3 (Standard) | ≥98% | Milbemycin A3 (Standard) is the analytical standard of Milbemycin A3 (HY-130423). This product is intended for research and analytical applications. Milbemycin A3 is a 16-membered macrocyclic lactone compound found in the soil bacterium Saccharopolyspora hygroscopicus subsp. aureolacrimosus. Milbemycin A3 enhances the opening of glutamate- and GABA-gated chloride channels and exhibits insecticidal activity. Milbemycin A3 can be used in insect resistance-related research. | ||||||||||||||||||||
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References
- [1]. Yang LY, et al. New nemadectin congeners with acaricidal and nematocidal activity from Streptomyces microflavus neau3 Y-3. Bioorg Med Chem Lett. 2013;23(20):5710-5713. [Content Brief]
- [2]. Nakagawa K, et al. Microbial conversion of milbemycins: hydroxylation of milbemycin A4 and related compounds by Cunninghamella echinulata ATCC 9244. J Antibiot (Tokyo). 1991;44(2):232-240. [Content Brief]
- [3]. Zhang J, et al. Genetic engineering of Streptomyces bingchenggensis to produce milbemycins A3/A4 as main components and eliminate the biosynthesis of nanchangmycin. Appl Microbiol Biotechnol. 2013;97(23):10091-10101. [Content Brief]
- [4]. Duke SO, et al. Natural toxins for use in pest management. Toxins (Basel). 2010;2(8):1943-1962. [Content Brief]
