54232-58-5
54232-58-5
Chemical Structure
(10E,12E)-9-Oxo-10,12-octadecadienoic acid
Synonym(s): 9-oxo-ODA
- CAS No.: 54232-58-5
- Formula:C18H30O3
- Molecular Weight:294.43
IUPAC Name: (10E,12E)-9-oxooctadeca-10,12-dienoic acid
InChIKey: LUZSWWYKKLTDHU-SIGMCMEVSA-N
SMILES: CCCCC/C=C/C=C/C(CCCCCCCC(O)=O)=O
Biological Activity: (10E,12E)-9-Oxo-10,12-octadecadienoic acid (9-oxo-ODA) is a PPARα agonist that can be isolated from the basidiomycete Gomphus floccosus. (10E,12E)-9-Oxo-10,12-octadecadienoic acid enhances fatty acid oxidation through PPARα activation, thereby inhibiting triglyceride accumulation. (10E,12E)-9-Oxo-10,12-octadecadienoic acid also has antifungal (Fungal) activity[1][2].
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(10E,12E)-9-Oxo-10,12-octadecadienoic acid | (10E,12E)-9-Oxo-10,12-octadecadienoic acid (9-oxo-ODA) is a PPARα agonist that can be isolated from the basidiomycete Gomphus floccosus. (10E,12E)-9-Oxo-10,12-octadecadienoic acid enhances fatty acid oxidation through PPARα activation, thereby inhibiting triglyceride accumulation. (10E,12E)-9-Oxo-10,12-octadecadienoic acid also has antifungal (Fungal) activity. | |||||||||||||||||||||
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References
- [1]. Cantrell CL, et al. Isolation and identification of antifungal fatty acids from the basidiomycete Gomphus floccosus. J Agric Food Chem. 2008 Jul 9;56(13):5062-8. [Content Brief]
- [2]. Kim YI, et al. Potent PPARα activator derived from tomato juice, 13-oxo-9,11-octadecadienoic acid, decreases plasma and hepatic triglyceride in obese diabetic mice. PLoS One. 2012;7(2):e31317. [Content Brief]
