552-72-7
552-72-7
Chemical Structure
Lobelanidine
- CAS 番号: 552-72-7
- Formula:C22H29NO2
- Molecular Weight:339.47
IUPAC Name: 2,2'-(1-methylpiperidine-2,6-diyl)bis(1-phenylethan-1-ol)
InChIKey: OWGJQNXIWMMDTH-COPRSSIGSA-N
SMILES: O[C@@H](C1=CC=CC=C1)C[C@@H]2N([C@@H](CCC2)C[C@@H](C3=CC=CC=C3)O)C
Biological Activity: Lobelanidine is an antagonist for nicotinic acetylcholine receptor (nAChR), which inhibits α7 nAChR response and α3β2/α3β4 nAChR responses, with IC50 of 2.8 and 8.2 μM[1].
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Lobelanidine | Lobelanidine is an antagonist for nicotinic acetylcholine receptor (nAChR), which inhibits α7 nAChR response and α3β2/α3β4 nAChR responses, with IC50 of 2.8 and 8.2 μM. | |||||||||||||||||||||
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References
Keywords
