55273-05-7
Chemical Structure
Impromidine
Synonym(s): SKF 92676
- CAS No.: 55273-05-7
- Formula:C14H23N7S
- Molecular Weight:321.44
IUPAC Name: 1-(3-(1H-imidazol-5-yl)propyl)-3-(2-(((4-methyl-1H-imidazol-5-yl)methyl)thio)ethyl)guanidine
InChIKey: MURRAGMMNAYLNA-UHFFFAOYSA-N
SMILES: N=C(NCCCC1=CN=CN1)NCCSCC2=C(C)N=CN2
Biological Activity: Impromidine (SKF 92676) is a potent agonist for histamine H2 receptor. Impromidine induces gastric mucosal blood flow and acid secretion[1][2].
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Impromidine | Impromidine (SKF 92676) is a potent agonist for histamine H2 receptor. Impromidine induces gastric mucosal blood flow and acid secretion. | |||||||||||||||||||||
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- [1]. Durant GJ, et al. Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors. Nature. 1978 Nov 23;276(5686):403-5. [Content Brief]
- [2]. McIsaac RL, et al. Gastric mucosal blood flow and acid secretory changes in man with impromidine: a new specific histamine-H2-receptor agonist. Gut. 1981 Jul;22(7):529-33. [Content Brief]
Keywords