5563-28-0
5563-28-0
Chemical Structure
JC-10
- CAS No.: 5563-28-0
- Formula:C25H29Cl2IN4
- Molecular Weight:583.34
InChIKey: WBMULJOQZAKELP-UHFFFAOYSA-M
SMILES: ClC1=CC=C2C(N(CC)/C(N2CC)=C/C=C/C3=[N+](CC)C4=C(C=C(C=C4)Cl)N3CC)=C1.[I-]
Biological Activity: JC-10 is a lipophilic mitochondrial membrane potential indicator and is a fluorescent dye. JC-10 accumulates and aggregates in healthy mitochondria to emit red fluorescence; exists as a monomer emitting green fluorescence in the cytosol or apoptotic cells with collapsed mitochondrial membrane potential, enabling measurement of mitochondrial depolarization via the green/red fluorescence ratio[1].
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JC-10 | 99.03% | JC-10 is a lipophilic mitochondrial membrane potential indicator and is a fluorescent dye. JC-10 accumulates and aggregates in healthy mitochondria to emit red fluorescence; exists as a monomer emitting green fluorescence in the cytosol or apoptotic cells with collapsed mitochondrial membrane potential, enabling measurement of mitochondrial depolarization via the green/red fluorescence ratio. | ||||||||||||||||||||
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