5638-76-6
5638-76-6
Chemical Structure
Betahistine
Synonym(s): OBE-101
- CAS No.: 5638-76-6
- Formula:C8H12N2
- Molecular Weight:136.19
IUPAC Name: N-methyl-2-(pyridin-2-yl)ethan-1-amine
InChIKey: UUQMNUMQCIQDMZ-UHFFFAOYSA-N
SMILES: CNCCC1=NC=CC=C1
Biological Activity: Betahistine is an orally active histamine H1 receptor agonist and a H3 receptor antagonist[1]. Betahistine is used for the study of rheumatoid arthritis (RA)[3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Betahistine | 99.84% | Betahistine is an orally active histamine H1 receptor agonist and a H3 receptor antagonist. Betahistine is used for the study of rheumatoid arthritis (RA). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.94
HY-B0524ARBetahistine dihydrochloride (Standard) -
Similarity Score 0.83
HY-W088717R2-(Pyridin-2-yl)ethan-1-ol (Standard) -
Similarity Score 0.83
HY-W013654N,N-Dimethyl-2-pyridineethylamine -
Similarity Score 0.82
HY-30170N-Methylphenethylamine -
Similarity Score 0.82
HY-34713N-Methylphenethylamine hydrochloride -
Similarity Score 0.80
HY-1075652-Pyridylethylamine hydrochloride -
Similarity Score 0.79
HY-W017453RN-Methyl-3-phenylpropan-1-amine (Standard) -
Similarity Score 0.77
HY-Y0004R2-Pyridinemethanol (Standard) -
Similarity Score 0.77
HY-13225ARivanicline -
Explore the MedChemAI to find more analogs
References
- [1]. Poyurovsky M, et al. The effect of betahistine, a histamine H1 receptor agonist/H3 antagonist, on olanzapine-induced weight gain in first-episode schizophrenia patients. Int Clin Psychopharmacol. 2005 Mar;20(2):101-3. [Content Brief]
- [3]. Tang KT, et al. Betahistine attenuates murine collagen-induced arthritis by suppressing both inflammatory and Th17 cell responses.Int Immunopharmacol. 2016 Oct;39:236-245. [Content Brief]
