56527-42-5
56527-42-5
Chemical Structure
5-Fluoro-4’-thiouridine
- CAS No.: 56527-42-5
- Formula:C9H11FN2O5S
- Molecular Weight:278.26
IUPAC Name: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione
InChIKey: FLAHATSCJQFZKB-UAKXSSHOSA-N
SMILES: O[C@H]1[C@@H](O)[C@H](N(C(N2)=O)C=C(F)C2=O)S[C@@H]1CO
Biological Activity: 5-Fluoro-4’-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5-Fluoro-4’-thiouridine | 5-Fluoro-4’-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
Keywords
