569649-11-2
569649-11-2
Chemical Structure
8-Hydroxy-2'-deoxyguanosine-15N5
- CAS No.: 569649-11-2
- Formula:C10H1315N5O5
- Molecular Weight:288.21
IUPAC Name: 2-(amino-15N)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7,9-dihydro-3H-purine-6,8-dione-15N4
InChIKey: HCAJQHYUCKICQH-JPVJISKASA-N
SMILES: O=C1[15N]([C@]2([H])O[C@@H]([C@H](C2)O)CO)C3=C(C([15N]=C([15NH]3)[15NH2])=O)[15NH]1
Biological Activity: 8-Hydroxy-2'-deoxyguanosine-15N5 is the 15N labeled 8-Hydroxy-2'-deoxyguanosine[1]. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis[2].
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8-Hydroxy-2'-deoxyguanosine-15N5 | 8-Hydroxy-2'-deoxyguanosine-15N5 is the 15N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis. | |||||||||||||||||||||
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8-Hydroxy-2'-deoxyguanosine (Standard) | 98.96% | 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis. | ||||||||||||||||||||
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8-Hydroxy-2'-deoxyguanosine-13C,15N2 | 8-Hydroxy-2'-deoxyguanosine-13C,15N2 is 13C and 15N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis. | |||||||||||||||||||||
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8-Hydroxy-2'-deoxyguanosine | 98.56% | 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Valavanidis A, et al. 8-hydroxy-2' -deoxyguanosine (8-OHdG): A critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2009 Apr;27(2):120-39. [Content Brief]
