57076-71-8
Chemical Structure
Denbufylline
Synonym(s): BRL 30892
- CAS No.: 57076-71-8
- Formula:C16H24N4O3
- Molecular Weight:320.39
IUPAC Name: 1,3-dibutyl-7-(2-oxopropyl)-3,7-dihydro-1H-purine-2,6-dione
InChIKey: HJPRDDKCXVCFOH-UHFFFAOYSA-N
SMILES: O=C(N1CCCC)N(CCCC)C2=C(N(CC(C)=O)C=N2)C1=O
Biological Activity: Denbufylline (BRL 30892) is an inhibitor of phosphodiesterase-4 (PDE4). Denbufylline is able to block the degradation of intracellular cAMP (cyclic adenosine phosphate) thereby increasing the level of intracellular cAMP, which helps regulate a variety of cellular functions. Denbufylline can be used in the study of chronic obstructive pulmonary disease (COPD), asthma and other inflammatory diseases[1].
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Denbufylline | 99.92% | Denbufylline (BRL 30892) is an inhibitor of phosphodiesterase-4 (PDE4). Denbufylline is able to block the degradation of intracellular cAMP (cyclic adenosine phosphate) thereby increasing the level of intracellular cAMP, which helps regulate a variety of cellular functions. Denbufylline can be used in the study of chronic obstructive pulmonary disease (COPD), asthma and other inflammatory diseases. | ||||||||||||||||||||
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Keywords
