57323-76-9
57323-76-9
Chemical Structure
KLK6-IN-2
- CAS No.: 57323-76-9
- Formula:C14H14N2O
- Molecular Weight:226.27
InChIKey: PWIUJBQMPRRSIX-UHFFFAOYSA-N
SMILES: NC(C1=CC=C(COC2=CC=CC=C2)C=C1)=N
Biological Activity: KLK6-IN-2 is a reversible non-covalent and selective KLK6 inhibitor, with an IC50 of 2.1 μM against hKLK6. KLK6-IN-2 acts as a reversible competitive inhibitor of boar Spermatozoa acrosin, with a Ki of 2.6 μM against porcine acrosin. KLK6-IN-2 exhibits trypanocidal activity against Trypanosoma brucei rhodesiense, with an IC50 of 3.71 μM[1].
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KLK6-IN-2 | KLK6-IN-2 is a reversible non-covalent and selective KLK6 inhibitor, with an IC50 of 2.1 μM against hKLK6. KLK6-IN-2 acts as a reversible competitive inhibitor of boar Spermatozoa acrosin, with a Ki of 2.6 μM against porcine acrosin. KLK6-IN-2 exhibits trypanocidal activity against Trypanosoma brucei rhodesiense, with an IC50 of 3.71 μM. | |||||||||||||||||||||
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