57469-92-8
Chemical Structure
(S)-Alaproclate hydrochloride
Synonym(s): (S)-GEA 654 hydrochloride; (S)-A03 hydrochloride
- CAS No.: 57469-92-8
- Formula:C13H19Cl2NO2
- Molecular Weight:292.20
IUPAC Name: 1-(4-chlorophenyl)-2-methylpropan-2-yl L-alaninate hydrochloride
InChIKey: OPAKSOWFKIUFNP-FVGYRXGTSA-N
SMILES: N[C@@H](C)C(OC(C)(C)CC1=CC=C(Cl)C=C1)=O.Cl
Biological Activity: (S)-Alaproclate ((S)-A03) hydrochloride is a potent selective serotonin reuptake inhibitor (SSRI), which is used as an antidepressant agent. (S)-Alaproclate (hydrochloride) also produces a potent block of N-methyl-d-aspartate (NMDA) receptor currents in hippocampal neurons (IC50=1.1 μM) with a potent blocker of K+ currents[1].
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(S)-Alaproclate hydrochloride | (S)-Alaproclate ((S)-A03) hydrochloride is a potent selective serotonin reuptake inhibitor (SSRI), which is used as an antidepressant agent. (S)-Alaproclate (hydrochloride) also produces a potent block of N-methyl-d-aspartate (NMDA) receptor currents in hippocampal neurons (IC50=1.1 μM) with a potent blocker of K+ currents. | |||||||||||||||||||||
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