57648-21-2
57648-21-2
Chemical Structure
Timiperone
- CAS No.: 57648-21-2
- Formula:C22H24FN3OS
- Molecular Weight:397.51
IUPAC Name: 1-(4-fluorophenyl)-4-(4-(2-thioxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)butan-1-one
InChIKey: YDLQKLWVKKFPII-UHFFFAOYSA-N
SMILES: S=C1NC2=CC=CC=C2N1C3CCN(CC3)CCCC(C4=CC=C(C=C4)F)=O
Biological Activity: Timiperone has a strong affinity for cerebral dopamine D2 receptor. Timiperone has antipsychotic activity, and inhibits stereotyped behaviour. Timiperone can be used for research of schizophrenia[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Timiperone | 99.23% | Timiperone has a strong affinity for cerebral dopamine D2 receptor. Timiperone has antipsychotic activity, and inhibits stereotyped behaviour. Timiperone can be used for research of schizophrenia. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Timiperone-d4 | Timiperone-d4 is the deuterium labeled Timiperone. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Sudo K, et al. Disposition of timiperone, 4'-fluoro-4-[4-(2-thioxo-1-benzimidazolinyl)piperidino]butyrophenone, a neuroleptic, in the rat on repeated oral dosage. Xenobiotica. 1981 Oct;11(10):685-91. [Content Brief]
- [2]. Kariya T, et al. A comparison of the clinical effects of timiperone, a new butyrophenone derivative, and haloperidol on schizophrenia using a double-blind technique. J Int Med Res. 1983;11(2):66-77.
- [3]. Inada, K., et al. First-Generation Antipsychotics as a Bridge to Second-Generation Antipsychotics in the Japanese Pharmaceutical Industry: Mosapramine, Timiperone, Zotepine, and Nemonapride. NeuroPsychopharmacotherapy. Springer, Cham. (2021).
Keywords
