579-23-7
Chemical Structure
Cyclovalone
Synonym(s): Beveno
- CAS. Nr.: 579-23-7
- Formula:C22H22O5
- Molecular Weight:366.41
IUPAC Name: 2,6-bis((E)-4-hydroxy-3-methoxybenzylidene)cyclohexan-1-one
InChIKey: DHKKONBXGAAFTB-OTYYAQKOSA-N
SMILES: O=C(/C(CCC/1)=C/C2=CC(OC)=C(O)C=C2)C1=C\C3=CC(OC)=C(O)C=C3
Biological Activity: Cyclovalone (Beveno) is a synthetic curcumin derivate, which inihibits cyclooxygenase and exhibits anti-inflammatory, antitumor and antioxidant activities[1]. Cyclovalone inhibits cell proliferation in normal and malignant prostatic cells. Cyclovalone ist orally active[2].
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Cyclovalone | 99.9% | Cyclovalone (Beveno) is a synthetic curcumin derivate, which inihibits cyclooxygenase and exhibits anti-inflammatory, antitumor and antioxidant activities. Cyclovalone inhibits cell proliferation in normal and malignant prostatic cells. Cyclovalone ist orally active. | ||||||||||||||||||||
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- [1]. Itokawa H, et al., Recent advances in the investigation of curcuminoids. Chin Med. 2008 Sep 17;3:11. [Content Brief]
- [2]. Markaverich BM, et al., Type II [3H]estradiol binding site antagonists: inhibition of normal and malignant prostate cell growth and proliferation. Int J Oncol. 1998 May;12(5):1127-35. [Content Brief]
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