58337-35-2
58337-35-2
Chemical Structure
Elliptinium acetate
Synonym(s): NSC 264137; Celiptium
- CAS No.: 58337-35-2
- Formula:C20H20N2O3
- Molecular Weight:336.38
IUPAC Name: 9-hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]carbazol-2-ium acetate
InChIKey: BOMZMNZEXMAQQW-UHFFFAOYSA-N
SMILES: O=C(C)[O-].OC1=CC=C2NC3=C(C)C4=C(C=[N+](C)C=C4)C(C)=C3C2=C1
Biological Activity: Elliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used in cancer research, particularly in metastatic breast cancer[1][2].
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Elliptinium acetate | Elliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used in cancer research, particularly in metastatic breast cancer. | |||||||||||||||||||||
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References
- [1]. Dugue B, et al. Covalent binding of elliptinium acetate (NSC 264137) to nucleic acids of L1210 cells in culture. Cancer Res. 1986 Aug;46(8):3828-33. [Content Brief]
- [2]. Arteaga CL, et al. Elliptinium, a DNA intercalating agent with broad antitumor activity in a human tumor cloning system. Eur J Cancer Clin Oncol. 1987 Nov;23(11):1621-6. [Content Brief]
Keywords
