Elliptinium acetate  (Synonyms: NSC 264137; Celiptium)

Elliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used in cancer research, particularly in metastatic breast cancer^[1][2].

Nucleic acids^[1][2].

Elliptinium (0.35 µM; 1 h) (9-OH-NME3) shows highly stable covalent bonding to nucleic acids of L1210 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

336.38

C₂₀H₂₀N₂O₃

58337-35-2

O=C(C)[O-].OC1=CC=C2NC3=C(C)C4=C(C=[N+](C)C=C4)C(C)=C3C2=C1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Dugue B, et al. Covalent binding of elliptinium acetate (NSC 264137) to nucleic acids of L1210 cells in culture. Cancer Res. 1986 Aug;46(8):3828-33.  [Content Brief]

  [2]. Arteaga CL, et al. Elliptinium, a DNA intercalating agent with broad antitumor activity in a human tumor cloning system. Eur J Cancer Clin Oncol. 1987 Nov;23(11):1621-6.  [Content Brief]