58717-24-1
Chemical Structure
A2315A
Synonym(s): Madumycin II; Antibiotic A 2315A
- CAS No.: 58717-24-1
- Formula:C26H37N3O7
- Molecular Weight:503.59
IUPAC Name: (12Z,4R,7R,8R,9Z,14E,16Z,18S,20R)-18,20-dihydroxy-7-isopropyl-4,8,16-trimethyl-6-oxa-3,12-diaza-1(4,2)-oxazolacyclohenicosaphane-9,14,16-triene-2,5,11-trione
InChIKey: SAQNYTQFLPVTNJ-HNSNWRLASA-N
SMILES: O=C(N[C@@H]1C)C2=COC(C[C@@H](C[C@@H](/C=C(\C=C\CNC(/C=C\[C@H]([C@H](OC1=O)C(C)C)C)=O)C)O)O)=N2
Biological Activity: A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic. A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation[1].
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A2315A | A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic. A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation. | |||||||||||||||||||||
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Keywords
