5909-24-0
5909-24-0
Chemical Structure
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
- CAS No.: 5909-24-0
- Formula:C8H9ClN2O2S
- Molecular Weight:232.69
IUPAC Name: ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
InChIKey: SNNHLSHDDGJVDM-UHFFFAOYSA-N
SMILES: O=C(OCC)C1=CN=C(SC)N=C1Cl
Biological Activity: Ethyl 4-chloro-2-(methylthio) pyrimidine-5-carboxylate is a pharmaceutical intermediate. Ethyl 4-chloro-2-(methylthio) pyrimidine-5-carboxylate can be used to synthesize inhibitors of various kinases (e.g., Cdk4, PDGF, FGF, EGF). Ethyl 4-chloro-2-(methylthio) pyrimidine-5-carboxylate is applicable to research related to cancer and fungal infections[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate | 99.85% | Ethyl 4-chloro-2-(methylthio) pyrimidine-5-carboxylate is a pharmaceutical intermediate. Ethyl 4-chloro-2-(methylthio) pyrimidine-5-carboxylate can be used to synthesize inhibitors of various kinases (e.g., Cdk4, PDGF, FGF, EGF). Ethyl 4-chloro-2-(methylthio) pyrimidine-5-carboxylate is applicable to research related to cancer and fungal infections. | ||||||||||||||||||||
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References
- [1]. Klutchko SR, et al. 2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity. J Med Chem. 1998 Aug 13;41(17):3276-92. [Content Brief]
- [2]. Barvian M, et al. Pyrido[2,3-d]pyrimidin-7-one inhibitors of cyclin-dependent kinases. J Med Chem. 2000 Nov 30;43(24):4606-16. [Content Brief]
- [3]. Wang S C, et al. Synthesis and antifungal activity evaluation of novel substituted pyrimidine‐5‐carboxamides bearing the pyridine moiety[J]. Journal of the Chinese Chemical Society, 2018, 65(4): 445-451.
