5909-24-0
5909-24-0
Chemical Structure
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
- CAS. Nr.: 5909-24-0
- Formula:C8H9ClN2O2S
- Molecular Weight:232.69
IUPAC Name: ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
InChIKey: SNNHLSHDDGJVDM-UHFFFAOYSA-N
SMILES: O=C(OCC)C1=CN=C(SC)N=C1Cl
Biological Activity: Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a drug intermediate. Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate can be used to synthesize inhibitors of various kinases such as Cdk4, PDGF, FGF, EGF[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate | 99.28% | Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a drug intermediate. Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate can be used to synthesize inhibitors of various kinases such as Cdk4, PDGF, FGF, EGF. | ||||||||||||||||||||
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References
- [1]. Barvian M, et al. Pyrido[2,3-d]pyrimidin-7-one inhibitors of cyclin-dependent kinases. J Med Chem. 2000 Nov 30;43(24):4606-16. [Content Brief]
- [2]. Klutchko SR, et al. 2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity. J Med Chem. 1998 Aug 13;41(17):3276-92. [Content Brief]
