6003-11-8
Chemical Structure
Alizarin 2-methyl ether
- CAS No.: 6003-11-8
- Formula:C15H10O4
- Molecular Weight:254.24
InChIKey: BYQWRZGQEZAOPQ-UHFFFAOYSA-N
SMILES: O=C1C2=C(C(C3=C(C(OC)=CC=C13)O)=O)C=CC=C2
Biological Activity: Alizarin 2-methyl ether is a DNA topoisomerase inhibitor. Alizarin 2-methyl ether inhibits the relaxation of supercoiled DNA via DNA topoisomerase I and II. Alizarin 2-methyl ether promotes adipocyte differentiation by increasing lipid accumulation. Alizarin 2-methyl ether possesses antidiabetic and insulin-sensitizing properties. Alizarin 2-methyl ether can be used in research related to human colon cancer, P-388 lymphocytic leukemia and diabetes[1][2][3].
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Alizarin 2-methyl ether | Alizarin 2-methyl ether is a DNA topoisomerase inhibitor. Alizarin 2-methyl ether inhibits the relaxation of supercoiled DNA via DNA topoisomerase I and II. Alizarin 2-methyl ether promotes adipocyte differentiation by increasing lipid accumulation. Alizarin 2-methyl ether possesses antidiabetic and insulin-sensitizing properties. Alizarin 2-methyl ether can be used in research related to human colon cancer, P-388 lymphocytic leukemia and diabetes. | |||||||||||||||||||||
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- [1]. Son JK, et al. Anticancer constituents from the roots of Rubia cordifolia L. Chemical & pharmaceutical bulletin. 2008 Feb;56(2):213-6. [Content Brief]
- [2]. Chang P, et al. Antitumor agents 50. 1 Morindaparvin-A, a new antileukemic anthraquinone, and alizarin-1-methyl ether from Morinda parvifolia, and the antileukemic activity of the related derivatives. J Nat Prod. 1982 Mar-Apr;45(2):206-10. [Content Brief]
- [3]. Liu Q, et al. Anthraquinones from Morinda officinalis roots enhance adipocyte differentiation in 3T3-L1 cells. Nat Prod Res. 2012;26(18):1750-4. [Content Brief]
Keywords
