Anticancer constituents from the roots of Rubia cordifolia L

  • Chem Pharm Bull (Tokyo). 2008 Feb;56(2):213-6. doi: 10.1248/cpb.56.213.
Jong Keun Son  1 ,  Soon Ja Jung ,  Ji Hyun Jung ,  Zhe Fang ,  Chong Soon Lee ,  Chang Seob Seo ,  Dong Cheul Moon ,  Byung Sun Min ,  Mi Ryeo Kim ,  Mi Hee Woo
Affiliations
  • 1. College of Pharmacy, Yeungnam University, Gyeongsan, Gyeongbuk, Korea.
PMID: 18239313 DOI: 10.1248/cpb.56.213
Abstract

Activity-directed isolation of the methylene chloride fraction of the roots of Rubia cordifolia L. resulted in the identification of a new epoxymollugin (3) and eight known compounds (1, 2, 4-9). The structures of the compounds were elucidated from chemical and spectroscopic evidence. In addition, their Topoisomerase I and II inhibitory activities and cytotoxicities were measured.

Products