60142-95-2
60142-95-2
Chemical Structure
Gabapentin hydrochloride
- CAS No.: 60142-95-2
- Formula:C9H18ClNO2
- Molecular Weight:207.70
IUPAC Name: 2-(1-(aminomethyl)cyclohexyl)acetic acid hydrochloride
InChIKey: XBUDZAQEMFGLEU-UHFFFAOYSA-N
SMILES: O=C(O)CC1(CN)CCCCC1.[H]Cl
Biological Activity: Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain[1][2][3].
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Gabapentin hydrochloride | 98.0% | Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain. | ||||||||||||||||||||
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Gabapentin hydrochloride (Standard) | ≥98% | Gabapentin (hydrochloride) (Standard) is the analytical standard of Gabapentin (hydrochloride). This product is intended for research and analytical applications. Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain. | ||||||||||||||||||||
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Gabapentin-d4 hydrochloride | Gabapentin-d4 hydrochloride is the deuterium labeled Gabapentin hydrochloride (HY-A0057A). Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain. | |||||||||||||||||||||
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Gabapentin-d6 hydrochloride | Gabapentin-d6 (hydrochloride) is deuterium labeled Gabapentin (hydrochloride). | |||||||||||||||||||||
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References
- [1]. Fink K, et, al. Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices. Br J Pharmacol. 2000 Jun;130(4):900-6. [Content Brief]
- [2]. Celikyurt IK, et, al. Gabapentin, A GABA analogue, enhances cognitive performance in mice. Neurosci Lett. 2011 Apr 1;492(2):124-8. [Content Brief]
- [3]. Meymandi MS, et, al. Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice. Eur J Anaesthesiol. 2008 Feb;25(2):129-34. [Content Brief]
